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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 1
1946 11
1947 14
1948 10
1949 14
1950 18
1951 19
1952 24
1953 32
1954 41
1955 65
1956 54
1957 74
1958 78
1959 72
1960 100
1961 114
1962 110
1963 286
1964 379
1965 308
1966 348
1967 434
1968 471
1969 550
1970 539
1971 639
1972 753
1973 755
1974 769
1975 690
1976 654
1977 623
1978 540
1979 608
1980 636
1981 656
1982 650
1983 643
1984 762
1985 851
1986 778
1987 823
1988 881
1989 942
1990 1076
1991 1104
1992 1080
1993 1102
1994 1259
1995 1262
1996 1179
1997 1199
1998 1248
1999 1388
2000 1529
2001 1556
2002 1572
2003 1556
2004 1590
2005 1608
2006 1739
2007 1817
2008 1921
2009 1821
2010 1865
2011 1907
2012 2092
2013 2044
2014 1952
2015 2026
2016 1912
2017 1855
2018 1652
2019 1500
2020 1437
2021 1289
2022 1142
2023 841
2024 332

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65,574 results

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Page 1
Current understanding of iron homeostasis.
Anderson GJ, Frazer DM. Anderson GJ, et al. Am J Clin Nutr. 2017 Dec;106(Suppl 6):1559S-1566S. doi: 10.3945/ajcn.117.155804. Epub 2017 Oct 25. Am J Clin Nutr. 2017. PMID: 29070551 Free PMC article. Review.
In the diet, iron is either sequestered within heme or in various nonheme forms. ...Cellular iron concentrations are modulated by the iron regulatory proteins (IRPs) IRP1 and IRP2. ...
In the diet, iron is either sequestered within heme or in various nonheme forms. ...Cellular iron concentrations are mo …
The role of iron in brain ageing and neurodegenerative disorders.
Ward RJ, Zucca FA, Duyn JH, Crichton RR, Zecca L. Ward RJ, et al. Lancet Neurol. 2014 Oct;13(10):1045-60. doi: 10.1016/S1474-4422(14)70117-6. Lancet Neurol. 2014. PMID: 25231526 Free PMC article. Review.
In the CNS, iron in several proteins is involved in many important processes such as oxygen transportation, oxidative phosphorylation, myelin production, and the synthesis and metabolism of neurotransmitters. Abnormal iron homoeostasis can induce cellular dam …
In the CNS, iron in several proteins is involved in many important processes such as oxygen transportation, oxidative phosphor …
Nonheme iron electron-transfer proteins.
Malkin R, Rabinowitz JC. Malkin R, et al. Annu Rev Biochem. 1967;36:113-48. doi: 10.1146/annurev.bi.36.070167.000553. Annu Rev Biochem. 1967. PMID: 18257717 Review. No abstract available.
Bio-inspired Nonheme Iron Oxidation Catalysis: Involvement of Oxoiron(V) Oxidants in Cleaving Strong C-H Bonds.
Kal S, Xu S, Que L Jr. Kal S, et al. Angew Chem Int Ed Engl. 2020 May 4;59(19):7332-7349. doi: 10.1002/anie.201906551. Epub 2020 Mar 2. Angew Chem Int Ed Engl. 2020. PMID: 31373120 Review.
Nonheme iron enzymes generate powerful and versatile oxidants that perform a wide range of oxidation reactions, including the functionalization of inert C-H bonds, which is a major challenge for chemists. ...In this Review, we highlight the recent spectroscopic and …
Nonheme iron enzymes generate powerful and versatile oxidants that perform a wide range of oxidation reactions, including the …
Nonheme-iron histochemistry for light and electron microscopy: a historical, theoretical and technical review.
Meguro R, Asano Y, Odagiri S, Li C, Iwatsuki H, Shoumura K. Meguro R, et al. Arch Histol Cytol. 2007 Apr;70(1):1-19. doi: 10.1679/aohc.70.1. Arch Histol Cytol. 2007. PMID: 17558140 Free article. Review.
We reviewed the methods of nonheme-iron histochemistry with special focus on the underlying chemical principles. The term nonheme-iron includes heterogeneous species of iron complexes where iron is more loosely bound to low-molecular weig …
We reviewed the methods of nonheme-iron histochemistry with special focus on the underlying chemical principles. The term n …
Oxygen activating nonheme iron enzymes.
Lange SJ, Que L Jr. Lange SJ, et al. Curr Opin Chem Biol. 1998 Apr;2(2):159-72. doi: 10.1016/s1367-5931(98)80057-4. Curr Opin Chem Biol. 1998. PMID: 9667935 Review.
Crystallographic data have established a 2-His-1-carboxylate facial triad as a structural motif common to a number of mononuclear nonheme iron enzymes, including isopenicillin N synthase, tyrosine hydroxylase and naphthalene dioxygenase. ...Finally, synthetic comple …
Crystallographic data have established a 2-His-1-carboxylate facial triad as a structural motif common to a number of mononuclear nonheme …
Repair of Iron Center Proteins-A Different Class of Hemerythrin-like Proteins.
Silva LSO, Matias PM, Romão CV, Saraiva LM. Silva LSO, et al. Molecules. 2022 Jun 23;27(13):4051. doi: 10.3390/molecules27134051. Molecules. 2022. PMID: 35807291 Free PMC article. Review.
Repair of Iron Center proteins (RIC) form a family of di-iron proteins that are widely spread in the microbial world. RICs contain a binuclear nonheme iron site in a four-helix bundle fold, two basic features of hemerythrin-like protei …
Repair of Iron Center proteins (RIC) form a family of di-iron proteins that are widely spread in the microbial w …
Mechanistic Insight on the Activity and Substrate Selectivity of Nonheme Iron Dioxygenases.
de Visser SP. de Visser SP. Chem Rec. 2018 Oct;18(10):1501-1516. doi: 10.1002/tcr.201800033. Epub 2018 Jun 7. Chem Rec. 2018. PMID: 29878456 Review.
Nonheme iron dioxygenases catalyze vital reactions for human health particularly related to aging processes. ...To this end, I will review recent work of our group on nonheme iron dioxygenases and include background information on their general structu …
Nonheme iron dioxygenases catalyze vital reactions for human health particularly related to aging processes. ...To this end, I …
Directed evolution of nonheme iron enzymes to access abiological radical-relay C(sp(3))-H azidation.
Rui J, Zhao Q, Huls AJ, Soler J, Paris JC, Chen Z, Reshetnikov V, Yang Y, Guo Y, Garcia-Borràs M, Huang X. Rui J, et al. Science. 2022 May 20;376(6595):869-874. doi: 10.1126/science.abj2830. Epub 2022 May 19. Science. 2022. PMID: 35587977 Free PMC article.
We report the reprogramming of nonheme iron enzymes to catalyze an abiological C(sp(3))-H azidation reaction through iron-catalyzed radical relay. ...Given the prevalence of radical relay reactions in organic synthesis and the diversity of nonheme i …
We report the reprogramming of nonheme iron enzymes to catalyze an abiological C(sp(3))-H azidation reaction through iron …
65,574 results
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